Police have launched a homicide investigation following the death of a woman in the Clutha settlement of Crichton, while another person remains in a critical condition.

Emergency services were called to a property on Adams Flat Road at about 6.10pm on Friday, after reports of a "serious incident".

One person is dead and another seriously injured after an incident on Adams Flat Road. Photo: Google Maps

Detective Sergeant Hayden Smale said a woman died at the scene, while a man was taken to hospital in a critical condition.

A scene guard remains in place at the address as police conduct a scene examination.

Police said there is not believed to be any risk to the public, but residents can expect an increased police presence in the Crichton area.